Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.64 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 7/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20539252 | 0.79 | ARG1 (1.00) | ARG1TLR8 | |
| SCHEMBL20539253 | 0.79 | ARG1 (1.00) | ARG1TLR8 | |
| SCHEMBL21062468 | 0.79 | ARG1 (1.00) | ARG1TLR8 | |
| SCHEMBL7373336 | 0.78 | TBXAS1 (0.44) | — | |
| SCHEMBL22147484 | 0.78 | ARG1 (0.76) | ARG1TLR8ALDH1A1KCNH2 | |
| SCHEMBL7377556 | 0.77 | ALDH1A1 (0.43) | ARG1ALDH1A1PLA2G4AF10F2 | |
| SCHEMBL7950828 | 0.76 | ALDH1A1 (0.42) | ALDH1A1PLA2G4AF10F2CES1 | |
| SCHEMBL7375810 | 0.76 | GSR (0.43) | ALDH1A1PLA2G4AF10F2CES1 | |
| SCHEMBL22923264 | 0.76 | ARG1 (0.72) | ARG1TLR8ALDH1A1KCNH2 | |
| SCHEMBL25471583 | 0.74 | ARG1 (0.71) | ARG1TLR8ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057314-A | ANTICOAGULANTS | BIOCHEM PHARMA INC. (CA) | 2000-05-02 | — | — | US | disclosed |
| CN-1175259-A | Low molecular weight bicyclic thrombin inhibitors | IAF BIOCHEM INT (CA) | 1998-03-04 | — | — | CN | disclosed |
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |