Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | MET | P08581 | 6/20 | 0.41 |
| ▸ | MST1R | Q04912 | 3/20 | 0.41 |
| ▸ | HPD | P32754 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 3/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HGF | P14210 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149096 | 0.91 | PDGFRA (0.45) | SRCTGFBR1METMST1RAXL | |
| SCHEMBL22149057 | 0.83 | SRC (0.41) | SRCTGFBR1METMST1RHPD | |
| SCHEMBL22149095 | 0.83 | SRC (0.40) | SRCTGFBR1METHPDPDGFRA | |
| SCHEMBL22149078 | 0.82 | TTR (0.40) | SRCTGFBR1METHPDAXL | |
| SCHEMBL22149058 | 0.79 | MGLL (0.39) | SRCTGFBR1METAXLMERTK | |
| SCHEMBL22148998 | 0.75 | PDGFRA (0.44) | SRCMETMST1RAXLMERTK | |
| SCHEMBL22149000 | 0.74 | KDR (0.36) | SRCTGFBR1METHPDAXL | |
| SCHEMBL22149107 | 0.73 | SRC (0.42) | SRCTGFBR1METHPDAXL | |
| SCHEMBL22149059 | 0.73 | MET (0.38) | SRCTGFBR1METAXLMERTK | |
| SCHEMBL22149064 | 0.72 | SRC (0.41) | SRCTGFBR1METHPDKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |