Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149078 | 0.86 | TTR (0.40) | SRCTGFBR1KDRHPDPDGFRA | |
| SCHEMBL22148992 | 0.83 | DOT1L (0.40) | SRCTGFBR1DOT1LKDRHPD | |
| SCHEMBL22149063 | 0.83 | SRC (0.47) | SRCTGFBR1KDRHPDPDGFRA | |
| SCHEMBL22149096 | 0.80 | PDGFRA (0.45) | SRCTGFBR1KDRFGFR2PDGFRA | |
| SCHEMBL22149092 | 0.80 | MGLL (0.39) | TGFBR1DOT1LKDRMET | |
| SCHEMBL22149064 | 0.74 | SRC (0.41) | SRCTGFBR1DOT1LKDRHPD | |
| SCHEMBL22149088 | 0.73 | DOT1L (0.37) | SRCTGFBR1DOT1LKDRFGFR2 | |
| SCHEMBL22149000 | 0.72 | KDR (0.36) | SRCTGFBR1KDRHPDPDGFRA | |
| SCHEMBL22149002 | 0.72 | MGLL (0.41) | SRCTGFBR1DOT1LKDRHPD | |
| SCHEMBL22149005 | 0.69 | TTR (0.40) | SRCTGFBR1KDRHPDPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |