Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22148987 | 0.84 | MGLL (0.41) | IDO1CYP3A4MGLL | |
| SCHEMBL22149067 | 0.81 | ABCB1 (0.44) | IDO1CYP3A4MGLLCYP2C9CYP2C19 | |
| SCHEMBL22149099 | 0.81 | MGLL (0.36) | IDO1MGLL | |
| SCHEMBL22129170 | 0.73 | JMJD6 (0.36) | IDO1CYP3A4MGLL | |
| SCHEMBL22149106 | 0.72 | MGLL (0.41) | IDO1MGLL | |
| SCHEMBL22946156 | 0.72 | KMT2A (0.43) | CYP2C19MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22149084 | 0.72 | MGLL (0.37) | IDO1MGLLCYP2C9CYP2C8CHRNA1 | |
| SCHEMBL22149287 | 0.72 | MGLL (0.40) | IDO1MGLL | |
| SCHEMBL22946326 | 0.70 | KMT2A (0.38) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL22149303 | 0.69 | IDO1 (0.41) | IDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |