Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946156 | 0.85 | KMT2A (0.43) | KMT2ALMNAHTTMEN1NPC1 | |
| SCHEMBL22946202 | 0.76 | L3MBTL1 (0.41) | KMT2ALMNAMEN1NPC1RAB9A | |
| SCHEMBL22945858 | 0.75 | KMT2A (0.33) | KMT2ALMNAHTTMEN1NPC1 | |
| SCHEMBL22946167 | 0.74 | TSHR (0.41) | KMT2ALMNAMEN1NPC1RAB9A | |
| SCHEMBL22946162 | 0.73 | MAPT (0.47) | KMT2ALMNAHTTMEN1NPC1 | |
| SCHEMBL23061289 | 0.72 | CNR1 (0.33) | KMT2ALMNAMEN1NPC1RAB9A | |
| SCHEMBL30253544 | 0.70 | ATF4 (0.42) | RAB9ASMN1; SMN2MAPTL3MBTL1KDM4E | |
| SCHEMBL22945860 | 0.68 | HCRTR1 (0.33) | KMT2ALMNAMEN1NPC1RAB9A | |
| SCHEMBL22946158 | 0.68 | KMT2A (0.48) | KMT2ALMNAHTTMEN1NPC1 | |
| SCHEMBL22945856 | 0.67 | TSHR (0.32) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018135-A1 | HETEROCYCLYL ALKYL SUBSTITUTED DICHLOROBENZOYL COMPOUNDS AND APPLICATIONS THEREOF | 东莞市东阳光农药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |