Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830233 | 0.88 | LCK (0.72) | KDM4EALDH1A1HPGDHSD17B10LCK | |
| SCHEMBL617928 | 0.88 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL978583 | 0.87 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| Hydrochloric Acid SCHEMBL7287472 | 0.86 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL9561825 | 0.86 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Hydrochloric Acid SCHEMBL8902783 | 0.86 | LCK (0.69) | KDM4EALDH1A1HPGDHSD17B10LCK | |
| SCHEMBL12444067 | 0.86 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10LCK | |
| SCHEMBL5695675 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL358180 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10LCK | |
| SCHEMBL8204839 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDHSD17B10LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912646-B2 | Transmembrane pores formed by aromatic oligoamide foldamers and uses of same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-02-27 | — | — | US | disclosed |
| US-20220380301-A9 | TRANSMEMBRANE PORES FORMED BY AROMATIC OLIGOAMIDE FOLDAMERS AND USES OF SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2022-12-01 | — | — | US | disclosed |
| US-20210355078-A1 | TRANSMEMBRANE PORES FORMED BY AROMATIC OLIGOAMIDE FOLDAMERS AND USES OF SAME | UNIV NEW YORK STATE RES FOUND (US) | 2021-11-18 | — | — | US | disclosed |
| US-11072578-B2 | Transmembrane pores formed by aromatic oligoamide foldamers and uses of same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-07-27 | — | — | US | disclosed |
| US-20200199066-A1 | TRANSMEMBRANE PORES FORMED BY AROMATIC OLIGOAMIDE FOLDAMERS AND USES OF SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355078-A1 | TRANSMEMBRANE PORES FORMED BY AROMATIC OLIGOAMIDE FOLDAMERS AND USES OF SAME | AQP1, STOM, SLC22A8 | KDM4E 4558/4885ALDH1A1 4354/4885HPGD 3751/4885 |
| US-11912646-B2 | Transmembrane pores formed by aromatic oligoamide foldamers and uses of same | AQP1, STOM, SLC22A8 | KDM4E 4558/4885ALDH1A1 4354/4885HPGD 3751/4885 |
| US-11072578-B2 | Transmembrane pores formed by aromatic oligoamide foldamers and uses of same | AQP1, STOM, SLC22A8 | KDM4E 4558/4885ALDH1A1 4354/4885HPGD 3751/4885 |
| US-20200199066-A1 | TRANSMEMBRANE PORES FORMED BY AROMATIC OLIGOAMIDE FOLDAMERS AND USES OF SAME | AQP1, STOM, SLC22A8 | KDM4E 4558/4885ALDH1A1 4354/4885HPGD 3751/4885 |
| US-20220380301-A9 | TRANSMEMBRANE PORES FORMED BY AROMATIC OLIGOAMIDE FOLDAMERS AND USES OF SAME | AQP1, STOM, SLC22A8 | KDM4E 4558/4885ALDH1A1 4354/4885HPGD 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.