Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.71 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.57 |
| ▸ | GABRP | O00591 | 8/20 | 0.57 |
| ▸ | GABRD | O14764 | 8/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.57 |
| ▸ | GABRE | P78334 | 8/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214367 | 0.88 | CNR2 (0.66) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL16120076 | 0.86 | CNR2 (0.85) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2214063 | 0.86 | CNR2 (0.77) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15706011 | 0.85 | CNR2 (0.54) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2214952 | 0.85 | HPGD (0.54) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2212394 | 0.84 | CNR2 (0.94) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5092382 | 0.84 | CNR2 (0.64) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL600437 | 0.83 | CNR2 (1.00) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10994093 | 0.83 | CNR2 (0.84) | CNR2GABRA1GABRG2GABRB3GABRA5 | |
| Hydrochloric Acid SCHEMBL27891826 | 0.83 | CNR2 (0.92) | CNR2GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | claimed |
| US-9425414-B2 | Organometallic complexes, and organic electroluminescence device and display using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-08-23 | — | — | US | disclosed |
| US-9425414-B2 | Organometallic complexes, and organic electroluminescence device and display using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-08-23 | — | — | US | disclosed |
| US-8772311-B2 | Harmine derivatives, intermediates used in their preparations, preparation processes and use thereof | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2014-07-08 | — | — | US | disclosed |
| US-20140124760-A1 | ORGANOMETALLIC COMPLEXES, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY USING THE SAME | CHEIL INDUSTRIES INC. (KR) | 2014-05-08 | — | — | US | disclosed |
| US-20140124760-A1 | ORGANOMETALLIC COMPLEXES, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY USING THE SAME | CHEIL INDUSTRIES INC. (KR) | 2014-05-08 | — | — | US | disclosed |
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
| EP-1634881-A1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | Xinjiang Huashidan Pharmaceutical Research Co., Ltd. (CN) | 2006-03-15 | — | — | EP | disclosed |
| EP-0110813-B1 | PROCESS FOR PRODUCING BETA-CARBOLINE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4705856-A | Process for producing β-carboline derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-11-10 | — | — | US | disclosed |
| EP-0110813-A2 | Process for producing beta-carboline derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | TPH1, HTR1F, TPH2 | CNR2 156/4885GABRA1 1401/4885GABRG2 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.