SCHEMBL22150983

SCHEMBL22150983

Clc1ccc2c(c1)C(c1ccccc1)(c1cccc(-c3ccccc3)c1)c1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 9/20 0.44
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
OPRK1 P41145 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
AKR1A1 P14550 1/20 0.40
AKR1B1 P15121 1/20 0.40
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
PGR P06401 2/20 0.36
CYP1A2 P05177 1/20 0.36
TDP2 O95551 1/20 0.36
SERPINE1 P05121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22151245 0.93 PDK2 (0.51) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL22151042 0.92 PDK2 (0.54) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL34464613 0.91 PDK2 (0.48) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL30716820 0.91 MEN1 (0.46) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL22173211 0.91 PDK2 (0.48) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL22150986 0.91 MEN1 (0.46) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL22173459 0.90 PDK2 (0.47) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL22173460 0.89 PDK2 (0.49) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL26574527 0.89 PDK2 (0.50) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL19850003 0.89 PDK2 (0.51) PDK2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363259-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11711972-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed
US-11711972-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed
WO-2020127145-A2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11711972-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof PPOX, ESR1, CCNE2 PDK2 1275/4885KDM4E 1749/4885MEN1 703/4885
US-20230363259-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME LAGE3, EML4, EPB41L2 PDK2 2527/4885KDM4E 523/4885MEN1 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.