Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 13/20 | 0.47 |
| ▸ | JAK1 | P23458 | 13/20 | 0.47 |
| ▸ | TYK2 | P29597 | 13/20 | 0.47 |
| ▸ | JAK3 | P52333 | 13/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121292 | 0.78 | JAK2 (0.45) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL22121213 | 0.77 | RORC (0.53) | KMT2A | |
| SCHEMBL19436566 | 0.74 | JAK2 (0.62) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19436506 | 0.74 | JAK2 (0.62) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19437503 | 0.74 | KMT2A (0.74) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL28063914 | 0.74 | JAK2 (0.46) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL22121416 | 0.73 | KMT2A (0.57) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL22121609 | 0.73 | JAK2 (0.51) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL22150565 | 0.73 | CHEK2 (0.48) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL21311021 | 0.73 | RPS6KB1 (0.57) | JAK2JAK1TYK2JAK3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |