Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | QPCT | Q16769 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22128414 | 0.81 | — | — | |
| SCHEMBL22152483 | 0.81 | ALDH1A1 (0.44) | PRPS1CNR2CNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22152007 | 0.81 | KDM1A (0.36) | PRPS1CNR2CNR1SMN1; SMN2GAA | |
| SCHEMBL22128369 | 0.79 | — | — | |
| SCHEMBL22128175 | 0.79 | — | — | |
| SCHEMBL22128239 | 0.79 | — | — | |
| SCHEMBL22128251 | 0.79 | — | — | |
| SCHEMBL22122373 | 0.79 | — | — | |
| SCHEMBL22128381 | 0.76 | — | — | |
| SCHEMBL31121473 | 0.74 | KRAS (0.36) | DUTPRPS1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | disclosed |