Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979747 | 0.93 | BRD4 (0.40) | LMNATP53HTTMAPTPTAFR | |
| SCHEMBL22128301 | 0.78 | POLB (0.53) | LMNAHTTMAPTTSHRGALR3 | |
| SCHEMBL22128352 | 0.77 | POLB (0.40) | LMNAHTTMAPTTSHRGALR3 | |
| SCHEMBL15206346 | 0.77 | DUT (0.45) | LMNATP53HTTMAPTDUT | |
| SCHEMBL22152198 | 0.77 | TSHR (0.48) | LMNATP53HTTMAPTTSHR | |
| SCHEMBL18496285 | 0.75 | BRD4 (0.60) | LMNATP53HTTMAPTGALR3 | |
| SCHEMBL29719369 | 0.75 | BRD4 (0.60) | LMNATP53HTTMAPTGALR3 | |
| SCHEMBL18732125 | 0.75 | ALDH1A1 (0.45) | LMNATP53HTTMAPTTSHR | |
| SCHEMBL18404171 | 0.75 | KDM4E (0.48) | LMNATP53HTTMAPTTSHR | |
| SCHEMBL1515046 | 0.74 | DUT (0.51) | LMNAHTTMAPTDUTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | disclosed |