Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22153148 | 0.84 | HPGD (0.37) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL22153166 | 0.84 | HPGD (0.37) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL29333155 | 0.82 | ALDH1A1 (0.33) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL22153137 | 0.76 | RGS4 (0.31) | — | |
| SCHEMBL22153693 | 0.73 | RGS4 (0.39) | ALDH1A1CYP2D6MAPK1KMT2A | |
| SCHEMBL22152325 | 0.71 | RGS4 (0.44) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL29332922 | 0.70 | RGS4 (0.36) | ALDH1A1GAACYP2D6HPGDNFKB1 | |
| SCHEMBL22153136 | 0.67 | ALDH1A1 (0.36) | ALDH1A1POLBKDM4EHPGDAPEX1 | |
| SCHEMBL22153150 | 0.65 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL22152338 | 0.64 | NSD2 (0.47) | ALDH1A1GAAPOLBKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125546-A1 | CONNECTOR FOR USE IN ANTIBODY MEDICAMENT CONJUGATE AND APPLICATIONS OF CONNECTOR | 荣昌生物制药（烟台）有限公司 | 2020-06-25 | — | — | WO | disclosed |