Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22153148 | 1.00 | HPGD (0.37) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL22153134 | 0.84 | ALDH1A1 (0.39) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL22153165 | 0.74 | RGS4 (0.39) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL8887852 | 0.74 | ALDH1A1 (0.34) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL29333155 | 0.70 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL24130616 | 0.70 | ALDH1A1 (0.64) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL30299434 | 0.70 | ALDH1A1 (0.64) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL21851961 | 0.70 | ALDH1A1 (0.64) | HPGDALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL22153693 | 0.69 | RGS4 (0.39) | ALDH1A1MAPK1CYP2D6MAPTCYP1A2 | |
| SCHEMBL22153155 | 0.69 | PTGS1 (0.43) | HPGDALDH1A1KDM4EMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125546-A1 | CONNECTOR FOR USE IN ANTIBODY MEDICAMENT CONJUGATE AND APPLICATIONS OF CONNECTOR | 荣昌生物制药（烟台）有限公司 | 2020-06-25 | — | — | WO | disclosed |