SCHEMBL2215314

SCHEMBL2215314

CCN(c1ccccc1)C(C)N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 3/20 0.41
TP53 P04637 1/20 0.41
TAAR1 Q96RJ0 5/20 0.40
SLC6A2 P23975 2/20 0.40
MAOA P21397 2/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
CYP2A6 P11509 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
CYP2D6 P10635 2/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4696702 0.98 MAPT (0.40) TSHRALDH1A1GLAMAPTTP53
SCHEMBL10939839 0.82 TSHR (0.43) TSHRALDH1A1GLAMAPTTP53
SCHEMBL2398343 0.82 TAAR1 (0.47) TSHRALDH1A1GLAMAPTTP53
SCHEMBL8649207 0.81 MAPT (0.40) TSHRALDH1A1GLAMAPTTP53
SCHEMBL317239 0.80 TAAR1 (0.46) TSHRALDH1A1GLAMAPTTP53
Hydrochloric Acid SCHEMBL8619260 0.79 MAPT (0.39) TSHRALDH1A1GLAMAPTTP53
SCHEMBL9001023 0.79 TP53 (0.45) TSHRALDH1A1MAPTTP53TAAR1
SCHEMBL415762 0.78 TSHR (0.45) TSHRALDH1A1GLAMAPTTP53
SCHEMBL8692711 0.78 TSHR (0.41) TSHRALDH1A1GLAMAPTTP53
SCHEMBL10650653 0.78 TSHR (0.41) TSHRALDH1A1GLAMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310533-B2 Ink composition containing a particular type of dye, and corresponding ink jet printing process AGFA GRAPHICS NV (BE) 2011-07-27 EP disclosed
EP-1717283-B1 Ink composition containing a particular type of dye, and corresponding ink jet printing process. AGFA GRAPHICS NV (BE) 2008-07-16 EP disclosed
EP-1310533-B1 Ink composition containing a particular type of dye, and corresponding ink jet printing process AGFA GEVAERT (BE) 2007-01-10 EP disclosed
EP-1717283-A1 Ink composition containing a particular type of dye, and corresponding ink jet printing process. Agfa-Gevaert (BE) 2006-11-02 EP disclosed
US-7025813-B2 Ink composition containing a particular type of dye, and corresponding ink-jet printing process AGFA-GEVAERT (BE) 2006-04-11 US disclosed
EP-1577356-A1 Ink composition containing a particular type of dye, and corresponding ink jet printing process. Agfa-Gevaert (BE) 2005-09-21 EP disclosed
US-20040206270-A1 Ink composition containing a particular type of dye, and corresponding ink-jet printing process AGFA GRAPHICS NV (BE) 2004-10-21 US disclosed
US-20030209166-A1 Ink composition containing a particular type of dye, and corresponding ink jet printing process AGFA-GEVAERT (BE) 2003-11-13 US disclosed
EP-1310533-A2 Ink composition containing a particular type of dye, and corresponding ink jet printing process Agfa-Gevaert (BE) 2003-05-14 EP disclosed
WO-1995002848-A1 MULTIFUNCTIONAL AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-26 WO disclosed
US-5116958-A Containing releasable oxime or lactam group CIBA-GEIGY CORPORATION (US) 1992-05-26 US disclosed
EP-0220284-B1 NOVEL FRUORESCENT COMPOUNDS AND BIOLOGICAL DIAGNOSTIC DEVICES POLAROID CORPORATION (US) 1990-01-31 EP disclosed
US-4886744-A REACTION PRODUCT CONTAINING DYE MOIETY POLAROID CORPORATION (US) 1989-12-12 US disclosed
EP-0220284-A1 NOVEL FRUORESCENT COMPOUNDS AND BIOLOGICAL DIAGNOSTIC DEVICES. POLAROID CORP (US) 1987-05-06 EP disclosed
WO-1986006374-A1 NOVEL FRUORESCENT COMPOUNDS AND BIOLOGICAL DIAGNOSTIC DEVICES POLAROID CORPORATION (US) 1986-11-06 WO disclosed
US-4268439-A Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed
US-4226784-A 2- and 5-Aminoalkylamino anthraquinone dyes useful as basic dyes in coloring hair L'OREAL (FR) 1980-10-07 US disclosed
US-4078886-A Sublimation transfer and diisocyanate fixation of amino- or hydroxy-containing anthraquinone dyestuffs and transfer sheets thereof CIBA-GEIGY AG (CH) 1978-03-14 US disclosed
US-3958933-A Process for the manufacture of fast dyeings on synthetic hydrophobic textile material CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed
US-3940246-A Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor CIBA-GEIGY AG (CH) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030209166-A1 Ink composition containing a particular type of dye, and corresponding ink jet printing process SNU13, SAMM50, SNX1 TSHR 4873/4885ALDH1A1 2702/4885GLA 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.