SCHEMBL8649207

SCHEMBL8649207

CCC(N)N(CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
GLA P06280 1/20 0.39
TAAR1 Q96RJ0 4/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NR1H2 P55055 3/20 0.35
NR1H3 Q13133 3/20 0.35
SLC6A2 P23975 2/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8619260 0.98 MAPT (0.39) MAPTTP53TSHRALDH1A1GLA
SCHEMBL11322173 0.82 TSHR (0.48) TP53TSHRALDH1A1TAAR1CYP2D6
SCHEMBL2215314 0.81 TSHR (0.41) MAPTTP53TSHRALDH1A1GLA
SCHEMBL4595133 0.80 HTR2A (0.43) MAPTTSHRALDH1A1GLATAAR1
Hydrochloric Acid SCHEMBL4696702 0.79 MAPT (0.40) MAPTTP53TSHRALDH1A1GLA
SCHEMBL8020762 0.78 ALDH1A1 (0.38) MAPTTP53TSHRALDH1A1GLA
SCHEMBL24090261 0.77 TSHR (0.41) MAPTTP53TSHRALDH1A1GLA
SCHEMBL3205909 0.77 SLC6A2 (0.44) MAPTTP53TSHRALDH1A1GLA
SCHEMBL2398343 0.76 TAAR1 (0.47) MAPTTP53TSHRALDH1A1GLA
SCHEMBL10939839 0.76 TSHR (0.43) MAPTTP53TSHRALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710012-A DETECTION OF CHOLESTEROL BY RELEASE OF HYDROGEN PEROXIDE ACTIMED LABORATORIES, INC. (US) 1998-01-20 US claimed
US-5710012-A DETECTION OF CHOLESTEROL BY RELEASE OF HYDROGEN PEROXIDE ACTIMED LABORATORIES, INC. (US) 1998-01-20 US disclosed
US-5518891-A SUBSTITUTED ANILINES, HYDRAZONES OR 4-AMINOANTIPYRINES ACTIMED LABORATORIES, INC. (US) 1996-05-21 US disclosed
EP-0082163-A1 ELECTROSTATIC, MAGNETIC DEVELOPERS, PREPARATION AND UTILIZATIONS THEREOF SUBLIGRAPHICS S.A. (CH) 1983-06-29 EP disclosed
WO-1983000235-A1 ELECTROSTATIC, MAGNETIC DEVELOPERS, PREPARATION AND UTILIZATIONS THEREOF HENDRIKS, DIETER 1983-01-20 WO disclosed
US-3987026-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1976-10-19 US disclosed