Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22153133 | 0.91 | RGS4 (0.38) | RGS4ALDH1A1KDM4ETP53GLA | |
| SCHEMBL22153155 | 0.91 | PTGS1 (0.43) | RGS4ALDH1A1KDM4ETP53GLA | |
| SCHEMBL22153132 | 0.82 | KDM4E (0.32) | ALDH1A1KDM4ETP53GLAPOLB | |
| SCHEMBL22152325 | 0.81 | RGS4 (0.44) | RGS4ALDH1A1KDM4ETP53GLA | |
| SCHEMBL8887852 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4ETP53GLAPOLB | |
| SCHEMBL29333225 | 0.80 | KDM4E (0.30) | ALDH1A1KDM4ETP53GLAPOLB | |
| SCHEMBL15433041 | 0.75 | PTGS1 (0.57) | RGS4ALDH1A1KDM4EHSD17B10HDAC1 | |
| SCHEMBL22153166 | 0.74 | HPGD (0.37) | ALDH1A1KDM4ETP53GLAPOLB | |
| SCHEMBL22153148 | 0.74 | HPGD (0.37) | ALDH1A1KDM4ETP53GLAPOLB | |
| SCHEMBL4852749 | 0.74 | PTGS1 (0.60) | RGS4KDM4ENFKB1HSD17B10HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3868409-B1 | THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS | REMEGEN CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020125546-A1 | CONNECTOR FOR USE IN ANTIBODY MEDICAMENT CONJUGATE AND APPLICATIONS OF CONNECTOR | 荣昌生物制药（烟台）有限公司 | 2020-06-25 | — | — | WO | disclosed |