Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19351675 | 0.85 | STAT3 (0.42) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL23127148 | 0.85 | ALDH1A1 (0.42) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL20826923 | 0.85 | GCK (0.42) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL19351655 | 0.85 | GCK (0.42) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL19319540 | 0.85 | GCK (0.42) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL23811941 | 0.84 | KMT2A (0.42) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL23811795 | 0.83 | ALDH1A1 (0.44) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL19324976 | 0.83 | HTT (0.39) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL20826983 | 0.81 | MAPT (0.46) | LMNAMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL23127281 | 0.80 | RAB9A (0.41) | LMNAMEN1ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934306-B2 | Hepatitis B antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| US-20200199143-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARM INC (US) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199143-A1 | HEPATITIS B ANTIVIRAL AGENTS | HAVCR2, PYGL, SLC10A1 | LMNA 453/4885MEN1 4731/4885ALDH1A1 3634/4885 |
| US-10934306-B2 | Hepatitis B antiviral agents | HAVCR2, PYGL, SLC10A1 | LMNA 453/4885MEN1 4731/4885ALDH1A1 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.