SCHEMBL22157152

SCHEMBL22157152

N#Cc1cc(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)cc1-c1c(F)cccc1F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.38
CYP11B2 P19099 4/20 0.38
CNR2 P34972 1/20 0.34
FLT3 P36888 1/20 0.34
ACLY P53396 1/20 0.34
TSPO P30536 1/20 0.33
MAP4K1 Q92918 1/20 0.32
NR3C1 P04150 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22156895 0.97 CYP11B1 (0.40) CYP11B1CYP11B2CNR2FLT3ACLY
SCHEMBL22157151 0.93 CYP11B1 (0.38) CYP11B1CYP11B2CNR2FLT3ACLY
SCHEMBL22156894 0.92 CYP11B1 (0.35) CYP11B1CYP11B2CNR2MAP4K1NR3C1
SCHEMBL22156559 0.91 CYP11B1 (0.39) CYP11B1CYP11B2CNR2FLT3ACLY
SCHEMBL22158523 0.91 CYP11B1 (0.42) CYP11B1CYP11B2CNR2MAP4K1NR3C1
SCHEMBL22156577 0.90 CYP11B1 (0.36) CYP11B1CYP11B2CNR2FLT3ACLY
SCHEMBL22155951 0.89 CYP11B1 (0.35) CYP11B1CYP11B2CNR2FLT3
SCHEMBL22156573 0.89 SLC6A9 (0.38) CYP11B1CYP11B2FLT3MAP4K1NR3C1
SCHEMBL20437450 0.88 TSPO (0.38) CYP11B1CYP11B2TSPOESR1ESR2
SCHEMBL22157140 0.88 CYP11B1 (0.36) CYP11B1CYP11B2CNR2MAP4K1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, OR51E2 CYP11B1 827/4885CYP11B2 531/4885CNR2 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.