SCHEMBL20437450

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20437453	0.93	TSPO (0.39)	TSPONPSR1MAOAMAOBCYP1A2
	SCHEMBL25138565	0.93	MAOA (0.41)	TSPONPSR1MAOAMAOBALDH1A1
	SCHEMBL19943062	0.90	NPSR1 (0.34)	TSPONPSR1CYP1A2CYP2C9CYP2C19
	SCHEMBL19909143	0.89	PIK3CA (0.41)	NPSR1CYP1A2CYP2C9CYP2C19CYP11B1
	SCHEMBL22156577	0.89	CYP11B1 (0.36)	TSPONPSR1MAOAMAOBCYP1A2
	SCHEMBL22760718	0.89	ALDH1A3 (0.40)	CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E
	SCHEMBL22563491	0.89	SQOR (0.36)	NPSR1CYP1A2CYP2C9CYP2C19CYP11B1
	SCHEMBL19909358	0.89	MYC (0.37)	NPSR1CYP1A2CYP2C9CYP2C19CYP11B1
	SCHEMBL22158513	0.89	CYP11B1 (0.36)	TSPOCYP11B1CYP11B2
	SCHEMBL20617280	0.89	TRPA1 (0.46)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.