SCHEMBL221580

SCHEMBL221580

C=C(C)C(=O)N1CCC(=O)C1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.38
NOTUM Q6P988 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
LIPE Q05469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4818987 0.88 LIPE (0.36) HSP90AA1NOTUMLIPE
SCHEMBL9474223 0.79 HSP90AA1 (0.42) HSP90AA1NOTUMLIPE
SCHEMBL7379323 0.79
SCHEMBL10350968 0.75 HSP90AA1 (0.40) HSP90AA1
SCHEMBL16281586 0.73 NOTUM (0.70) NOTUM
SCHEMBL269621 0.73 TDP1 (0.42) TDP1
SCHEMBL236549 0.73
SCHEMBL60542 0.72
SCHEMBL17929144 0.72 LIPE (0.35) NOTUMLIPE
Ammonia Solution, Strong SCHEMBL27931519 0.70 HSP90AA1 (0.42) HSP90AA1NOTUMLIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
US-20090060597-A1 COPOLYMER, RESIN FOR ELECTROPHOTOGRAPHIC FUNCTIONAL COMPONENT PARTS, DEVELOPING ROLLER, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KASEI KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed