Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60542 | 0.83 | — | — | |
| SCHEMBL10350968 | 0.82 | HSP90AA1 (0.40) | HSP90AA1 | |
| Ammonia Solution, Strong SCHEMBL27931519 | 0.81 | HSP90AA1 (0.42) | HSP90AA1PKMKMT2APOLBLIPE | |
| SCHEMBL221580 | 0.79 | HSP90AA1 (0.38) | HSP90AA1LIPENOTUM | |
| SCHEMBL11748418 | 0.76 | — | — | |
| SCHEMBL7379323 | 0.76 | — | — | |
| SCHEMBL24120035 | 0.74 | LIPE (0.38) | HSP90AA1PKMKMT2APOLBLIPE | |
| SCHEMBL362028 | 0.72 | PKM (0.40) | HSP90AA1PKMKMT2APOLBLIPE | |
| SCHEMBL7469385 | 0.71 | HPGD (0.56) | HPGDSMN1; SMN2 | |
| SCHEMBL10124069 | 0.71 | ESR1 (0.50) | HSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | claimed |
| JP-5112525-A | — | — | None | — | — | JP | disclosed |
| JP-H05112525-A | PREPARATION OF 4-HYDROXY-2-OXO-PYRROLIDIN-1-YL-ACETAMIDE | LONZA AG | 1993-05-07 | — | — | JP | disclosed |
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | disclosed |
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | disclosed |