⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27931519 | 0.98 | HSP90AA1 (0.42) | — | |
| SCHEMBL217162 | 0.86 | HSP90AA1 (0.34) | — | |
| SCHEMBL362028 | 0.84 | PKM (0.40) | — | |
| SCHEMBL2573205 | 0.84 | TRIM24 (0.38) | — | |
| SCHEMBL9474223 | 0.83 | HSP90AA1 (0.42) | — | |
| SCHEMBL670641 | 0.78 | — | — | |
| SCHEMBL4772854 | 0.78 | NOTUM (0.31) | — | |
| SCHEMBL7379323 | 0.78 | — | — | |
| SCHEMBL11748418 | 0.78 | — | — | |
| SCHEMBL784996 | 0.76 | TRIM24 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284080-A | Dihydropyrimidine derivative containing boric acid and boric acid pinacol ester group, and preparation method and application thereof | 山东大学 | 2023-06-23 | — | — | CN | claimed |
| EP-4532497-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | Jazz Pharmaceuticals Ireland Limited (IE) | 2025-04-09 | — | — | EP | disclosed |
| CN-119233976-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-118666734-A | Honokiol derivative and preparation method and application thereof | 上海植瑞新成医药科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118556059-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20240228437-A1 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-07-11 | — | — | US | disclosed |
| EP-4395890-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| EP-4346898-A1 | METHODS FOR INHIBITING RAS | Revolution Medicines, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2024067660-A1 | AZA-FUSED RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 苏州爱科百发生物医药技术有限公司 | 2024-04-04 | — | — | WO | disclosed |
| WO-2024072930-A1 | DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20020077337-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2002-06-20 | — | — | US | disclosed |
| US-20020025567-A1 | Microbial process for preparation of optically active 3-hydroxypyrrolidine derivatives | WONG JOHN W (US) | 2002-02-28 | — | — | US | disclosed |
| WO-2001077101-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-10-18 | — | — | WO | disclosed |
| EP-1130109-A1 | Microbial process for preparation of optically active 3-Hydroxypyrrolidine derivatives | Pfizer Products Inc. (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0921800-A4 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL MYERS SQUIBB CO (US) | 2000-12-06 | — | — | EP | disclosed |
| CN-1267303-A | 3-substituted 3,4,5, 7-tetrahydropyrrolo [3 ', 4': 4,5] thieno [2, 3-d ] pyrimidine derivatives, their preparation and use as 5HT antagonists | BASF AG (DE) | 2000-09-20 | — | — | CN | disclosed |
| EP-0921800-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| CN-1204327-A | Pharmaceutically active quinazoline compounds | ASTRA PHARMA PROD (GB) | 1999-01-06 | — | — | CN | disclosed |
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997029748-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-21 | — | — | WO | disclosed |