Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21852155 | 0.80 | POLB (0.40) | GABRA1GABRB2POLBALDH1A1MAPT | |
| SCHEMBL6564003 | 0.77 | DDR1 (0.43) | POLBALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL15994814 | 0.77 | GABRA1 (0.48) | GABRA1GABRB2FEN1ALDH1A1MAPT | |
| SCHEMBL20640459 | 0.77 | POLB (0.38) | POLBALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL25457914 | 0.77 | ALDH1A1 (0.38) | POLBALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL14370499 | 0.74 | ERCC1 (0.45) | GABRA1GABRB2CTRCESR1ESR2 | |
| SCHEMBL31569145 | 0.74 | CTRC (0.38) | GABRA1GABRB2POLBALDH1A1MAPT | |
| SCHEMBL9410519 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2CTRCPRKCI | |
| SCHEMBL45861 | 0.74 | GABRA1 (0.68) | GABRA1GABRB2FEN1CTRCESR1 | |
| SCHEMBL9505579 | 0.73 | GABRA1 (0.54) | GABRA1GABRB2FEN1POLBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473024-B1 | Dyeing composition comprising 2-chloro 6-methyl 3-amino phenol | OREAL (FR) | 2011-07-27 | — | — | EP | claimed |