Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214017 | 0.91 | POLB (0.40) | POLBKDM4CALOX15ALDH1A1HPGD | |
| SCHEMBL2213028 | 0.88 | POLB (0.42) | POLBKDM4CALOX15ALDH1A1HPGD | |
| SCHEMBL2215670 | 0.81 | CNR2 (0.43) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29217020 | 0.80 | KDM4E (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2214060 | 0.79 | ALDH1A1 (0.48) | POLBALOX15ALDH1A1HPGDPTGER4 | |
| SCHEMBL2215825 | 0.78 | POLB (0.43) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2216277 | 0.78 | CNR2 (0.43) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2214735 | 0.76 | CYP19A1 (0.47) | POLBALDH1A1HPGDKDM4EMAPK1 | |
| SCHEMBL2218129 | 0.75 | PGR (0.47) | ALDH1A1HPGD | |
| SCHEMBL2217196 | 0.74 | MEN1 (0.43) | ALDH1A1HPGDKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | claimed |