Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216828 | 0.92 | PGR (0.46) | PGRRORARORCRORBCNR2 | |
| SCHEMBL2214060 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGD | |
| SCHEMBL2215558 | 0.87 | CNR2 (0.50) | PGRRORARORCRORBCNR2 | |
| SCHEMBL2214735 | 0.85 | CYP19A1 (0.47) | ALDH1A1HPGD | |
| SCHEMBL27899805 | 0.85 | CNR2 (0.48) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2214021 | 0.84 | PLA2G2A (0.43) | CNR2ALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL27917571 | 0.84 | CNR2 (0.45) | PGRRORARORCRORBCNR2 | |
| SCHEMBL29217020 | 0.84 | KDM4E (0.46) | ALDH1A1HPGD | |
| SCHEMBL2215730 | 0.84 | ALDH1A1 (0.43) | CNR2ALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL27899832 | 0.83 | CNR2 (0.53) | CNR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | claimed |