Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 2/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556803 | 0.90 | MRGPRX4 (0.71) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL7469360 | 0.90 | MRGPRX4 (0.71) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL9360159 | 0.89 | MRGPRX4 (0.78) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL28336349 | 0.89 | MRGPRX4 (0.69) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL7943998 | 0.87 | FOLH1 (0.57) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL2634130 | 0.85 | NR4A2 (0.63) | RAB9ASMN1; SMN2NPC1MRGPRX4PLA2G4B | |
| SCHEMBL23692893 | 0.84 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL7900610 | 0.84 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL12968385 | 0.84 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 | |
| SCHEMBL29032420 | 0.84 | SMN1; SMN2 (0.61) | RAB9ASMN1; SMN2NPC1POLBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207744-A1 | DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA | EXPANSION THERAPEUTICS, INC. | 2020-07-02 | — | — | US | disclosed |
| US-20200207744-A1 | DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA | EXPANSION THERAPEUTICS, INC. | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207744-A1 | DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA | HNRNPH1, HNRNPUL2, HNRNPH3 | RAB9A 2880/4885SMN1; SMN2 32/4885NPC1 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.