Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.63 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 3/20 | 0.55 |
| ▸ | RXRB | P28702 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943998 | 0.89 | FOLH1 (0.57) | NR4A2FOLH1RXRARXRBHPGD | |
| SCHEMBL28877521 | 0.88 | KMT2A (0.57) | NR4A2NR4A1NR4A3SRD5A2MCL1 | |
| SCHEMBL1649243 | 0.87 | FOLH1 (0.68) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL1600077 | 0.87 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL29556736 | 0.87 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL4756552 | 0.85 | MAOB (0.63) | NR4A2NR4A1NR4A3SRD5A2MCL1 | |
| SCHEMBL5583147 | 0.85 | MCL1 (0.63) | NR4A2NR4A1NR4A3MCL1MEN1 | |
| Hydrochloric Acid SCHEMBL10857748 | 0.85 | MRGPRX4 (0.61) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL22160247 | 0.85 | RAB9A (0.68) | PTGER1FOLH1RXRARXRBPLA2G4B | |
| SCHEMBL10089235 | 0.84 | FOLH1 (0.69) | NR4A2NR4A1NR4A3SRD5A2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484950-A | Agents for use in the treatment of tissue damage | UCL商业有限责任公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115484949-A | Agent 2 for use in the treatment of tissue damage | UCL商业有限责任公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-102482294-B | Complicated mixed ligand open-framework material | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-03 | — | — | CN | disclosed |
| CN-102482294-A | Complex mixed ligand open framework materials | UNIV CALIFORNIA | 2012-05-30 | — | — | CN | disclosed |
| EP-2438073-A2 | COMPLEX MIXED LIGAND OPEN FRAMEWORK MATERIALS | The Regents Of The University Of California (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010148296-A2 | COMPLEX MIXED LIGAND OPEN FRAMEWORK MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-23 | — | — | WO | disclosed |