Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530176 | 0.92 | KCNA3 (0.50) | KCNA3 | |
| SCHEMBL4219044 | 0.91 | LSS (0.59) | HRH3LSSKCNA3HRH1HDAC3 | |
| SCHEMBL5419110 | 0.91 | RARB (0.51) | CYP3A4CYP2D6HRH3KCNA3RARB | |
| SCHEMBL11178061 | 0.89 | DRD4 (0.50) | HRH3HRH1KCNH2 | |
| SCHEMBL11613225 | 0.87 | KCNA3 (0.52) | CYP2D6HRH3KCNA3KCNH2 | |
| SCHEMBL15810293 | 0.86 | MMP2 (0.58) | HRH3HRH1HDAC1HDAC2 | |
| SCHEMBL7147877 | 0.85 | KDM4E (0.49) | CYP3A4CYP2D6HRH3LSSRARB | |
| SCHEMBL4892264 | 0.85 | KCNA3 (0.58) | HRH3LSSKCNA3HRH1HDAC3 | |
| SCHEMBL12517712 | 0.84 | GSTP1 (0.53) | CYP3A4CYP2D6HRH3LSSCYP1A2 | |
| SCHEMBL11615899 | 0.84 | KCNA3 (0.55) | CYP2D6HRH3KCNA3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431039-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120002141-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120002141-A1 | MESOGENIC STABILIZERS | BMI1, METTL14, PYM1 | CYP3A4 3686/4885CYP2D6 3875/4885HRH3 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.