Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738201 | 0.92 | ALDH1A1 (0.35) | — | |
| SCHEMBL22164343 | 0.83 | KDM4E (0.33) | — | |
| SCHEMBL15957809 | 0.81 | HCRTR1 (0.32) | — | |
| SCHEMBL30311372 | 0.79 | DPP4 (0.33) | — | |
| SCHEMBL22164346 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL22175842 | 0.79 | GPR119 (0.36) | PDE10A | |
| SCHEMBL30311324 | 0.79 | GPR119 (0.36) | PDE10A | |
| SCHEMBL30311192 | 0.78 | NR1H2 (0.33) | — | |
| SCHEMBL2738204 | 0.76 | MAPT (0.33) | — | |
| SCHEMBL2737925 | 0.73 | GPR119 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138015-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | 大正製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |