Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22175842 | 0.86 | GPR119 (0.36) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL30311324 | 0.86 | GPR119 (0.36) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL22164266 | 0.83 | PDE10A (0.33) | — | |
| SCHEMBL2738201 | 0.74 | ALDH1A1 (0.35) | ALDH1A1LMNAHTTNPSR1L3MBTL1 | |
| SCHEMBL30311192 | 0.74 | NR1H2 (0.33) | ALDH1A1 | |
| SCHEMBL30311147 | 0.73 | DPP4 (0.35) | KDM4EALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL2737925 | 0.73 | GPR119 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL15957792 | 0.72 | SIGMAR1 (0.49) | — | |
| SCHEMBL21279836 | 0.66 | HCRTR1 (0.37) | — | |
| SCHEMBL15764138 | 0.65 | NPC1 (0.37) | KDM4EALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138015-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | 大正製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |