Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245676 | 0.88 | CYP2D6 (0.60) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL3654740 | 0.86 | CYP2D6 (0.61) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL2420657 | 0.84 | MAPT (0.44) | CYP2D6CYP2C9CYP2C19HIF1ATSHR | |
| SCHEMBL28467253 | 0.84 | CYP2D6 (0.41) | CYP2D6CYP2C9CYP2C19HIF1ATSHR | |
| SCHEMBL16415925 | 0.81 | HIF1A (0.39) | CYP2D6CYP2C9CYP2C19HIF1ATSHR | |
| SCHEMBL7696506 | 0.81 | CYP2D6 (0.49) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL1866738 | 0.79 | CYP2D6 (0.47) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13681637 | 0.79 | CYP2D6 (0.47) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL5682017 | 0.79 | CYP2D6 (0.47) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL27545267 | 0.79 | CYP2D6 (0.47) | CYP2D6TSHRALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382306-B2 | Octapeptide compounds derived from somatostatin and the therapeutic use thereof | IPSEN PHARMA S.A.S. (FR) | 2016-07-05 | — | — | US | disclosed |
| US-20110178013-A1 | NOVEL OCTAPEPTIDE COMPOUNDS DERIVED FROM SOMATOSTATIN AND THE THERAPEUTIC USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2011-07-21 | — | — | US | disclosed |
| EP-0163284-B1 | SUBSTITUTED CHROMANON-2-YL ALKANOLS AND DERIVATIVES THEREOF | G.D. Searle & Co. (US) | 1989-01-04 | — | — | EP | disclosed |
| EP-0163284-A2 | Substituted chromanon-2-yl alkanols and derivatives thereof | G.D. Searle & Co. (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4546194-A | Substituted chromanon-2-yl alkanols and derivatives thereof | G. D. SEARLE & CO. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4125713-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125712-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4013688-A | STEROIDS | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3948981-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
| US-3933891-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3931284-A | 11β-PGE2 compounds | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931283-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178013-A1 | NOVEL OCTAPEPTIDE COMPOUNDS DERIVED FROM SOMATOSTATIN AND THE THERAPEUTIC USE THEREOF | SSTR5, SSTR1, SSTR3 | CYP2D6 1821/4885CYP2C9 3614/4885CYP2C19 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.