SCHEMBL7696506

SCHEMBL7696506

CCCC(=O)C(CC(=O)OCC)C1CCCC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.49
TSHR P16473 2/20 0.38
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 3/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.35
SMYD3 Q9H7B4 1/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
NAAA Q02083 2/20 0.34
UGT2B7 P16662 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3654740 0.83 CYP2D6 (0.61) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL1245676 0.82 CYP2D6 (0.60) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL2216450 0.81 CYP2D6 (0.51) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL1245653 0.76 CYP2D6 (0.56) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL14975944 0.74 NPSR1 (0.38) TSHRALDH1A1NPSR1NAAA
SCHEMBL1866738 0.73 CYP2D6 (0.47) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL22963812 0.73 CYP2D6 (0.47) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL5682017 0.73 CYP2D6 (0.47) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL13681637 0.73 CYP2D6 (0.47) CYP2D6TSHRKMT2AALDH1A1NPSR1
SCHEMBL27545267 0.73 CYP2D6 (0.47) CYP2D6TSHRKMT2AALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344471-B1 DIISOPROPYL FLUOROPHOSPHATE (DFP), TREATMENT OF COGNITIVE DISORDERS, DEPRESSION, SCHIZOPHRENIA AND ANXIETY. BAYER AKTIENGESELLSCHAFT (DE) 2002-02-05 US disclosed