Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 17/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936324 | 1.00 | CYP1B1 (0.65) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL10262375 | 0.92 | CYP1B1 (0.60) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL30459062 | 0.88 | CYP1B1 (0.53) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL15096386 | 0.88 | CYP1B1 (0.53) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL30455266 | 0.88 | CYP1B1 (0.53) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL10267887 | 0.87 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL10262179 | 0.86 | ALDH1A1 (0.56) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL26243132 | 0.84 | CYP1B1 (0.70) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL21988061 | 0.83 | CYP1B1 (0.58) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL10267895 | 0.83 | CYP1B1 (0.58) | CYP1B1ALDH1A1POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883924-A2 | METHODS FOR MAKING DIMERIC NAPHTHALIMIDES AND SOLID STATE FORMS OF THE SAME | Alucent Biomedical, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| WO-2020139971-A2 | METHODS FOR MAKING DIMERIC NAPHTHALIMIDES AND SOLID STATE FORMS OF THE SAME | Alucent Biomedical, Inc. (US) | 2020-07-02 | — | — | WO | disclosed |