Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 17/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459062 | 1.00 | CYP1B1 (0.53) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL15096386 | 1.00 | CYP1B1 (0.53) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL29936324 | 0.88 | CYP1B1 (0.65) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL22164834 | 0.88 | CYP1B1 (0.65) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL26349189 | 0.84 | MGMT (0.42) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL29199650 | 0.82 | HPGD (0.49) | ALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL10262375 | 0.81 | CYP1B1 (0.60) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL14499669 | 0.80 | HPGD (0.50) | ALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL15096384 | 0.80 | MEN1 (0.57) | ALDH1A1POLBKDM4EMEN1NPC1 | |
| SCHEMBL10267887 | 0.77 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192468-A2 | HETEROARYL AND HETEROCYCLYL COMPOUNDS | Sigilon Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |