Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092638 | 0.82 | HNF4A (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1115139 | 0.77 | CYP1A2 (0.43) | ALDH1A1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL29844508 | 0.77 | CDK5 (0.37) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL29844446 | 0.77 | CDK5 (0.37) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL275596 | 0.77 | CDK5 (0.37) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL1230997 | 0.76 | HTR2A (0.47) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL29844647 | 0.76 | HTR2A (0.47) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL27734241 | 0.75 | CDK5 (0.36) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| Hydrochloric Acid SCHEMBL1114916 | 0.75 | CDK5 (0.36) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL12009206 | 0.74 | MEN1 (0.47) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695435-B2 | Composition comprising a polymeric reagent | NEKTAR THERAPEUTICS (US) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10695435-B2 | Composition comprising a polymeric reagent | CD44, FCGRT, C9 | ALDH1A1 898/4885MAPT 1479/4885MEN1 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.