Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583741 | 0.87 | KEAP1 (0.49) | HNF4AALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL4624902 | 0.83 | ALDH1A1 (0.39) | HNF4AALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL10085227 | 0.83 | ALDH1A1 (0.45) | HNF4AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL22166256 | 0.82 | ALDH1A1 (0.38) | HNF4AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL28482428 | 0.82 | HNF4A (0.45) | HNF4AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL8399565 | 0.81 | FABP5 (0.39) | ALDH1A1L3MBTL1LMNAKMT2AFABP5 | |
| SCHEMBL1934919 | 0.80 | ALDH1A1 (0.43) | HNF4AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL7724549 | 0.79 | ALDH1A1 (0.45) | HNF4AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL16253851 | 0.77 | KMT2A (0.51) | ALDH1A1L3MBTL1LMNAMAPTMYC | |
| SCHEMBL3062707 | 0.77 | HTR2A (0.47) | MAPTKMT2AFABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11406618-B2 | Polymer-des-ethyl sunitinib conjugates | NEKTAR THERAPEUTICS (US) | 2022-08-09 | — | — | US | disclosed |
| US-20190142798-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS | 2019-05-16 | — | — | US | disclosed |
| US-20190142798-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS | 2019-05-16 | — | — | US | disclosed |
| US-10220020-B2 | Polymer-des-ethyl sunitinib conjugates | NEKTAR THERAPEUTICS (US) | 2019-03-05 | — | — | US | disclosed |
| US-10220020-B2 | Polymer-des-ethyl sunitinib conjugates | NEKTAR THERAPEUTICS (US) | 2019-03-05 | — | — | US | disclosed |
| EP-2654797-B1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2654797-B1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20140039030-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140039030-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140039030-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-02-06 | — | — | US | disclosed |
| EP-2654797-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | Nektar Therapeutics (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088522-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2012-06-28 | — | — | WO | disclosed |
| US-6046306-A | SOLID PHASE SYNTHESIS OF PEPTIDE NUCLEIC ACIDS ALLOWING OLIGOMER TO BE CLEAVED OFF FROM THE SOLID SUPPORT UNDER THE ALKALINE CONDITIONS CONVENTIONALLY USED FOR OLIGONUCLEOTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0672700-B1 | PNA-synthesis using an aminoprotecting group which is labile against weak acids | HOECHST AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0672700-A1 | PNA-synthesis using an aminoprotecting group which is labile against weak acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10220020-B2 | Polymer-des-ethyl sunitinib conjugates | KDR, FLT4, FLT1 | HNF4A 3345/4885ALDH1A1 3041/4885L3MBTL1 3148/4885 |
| US-11406618-B2 | Polymer-des-ethyl sunitinib conjugates | KDR, FLT4, FLT1 | HNF4A 3345/4885ALDH1A1 3041/4885L3MBTL1 3148/4885 |
| US-20140039030-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | KDR, FLT4, FLT1 | HNF4A 3345/4885ALDH1A1 3041/4885L3MBTL1 3148/4885 |
| US-20190142798-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | KDR, FLT4, FLT1 | HNF4A 3345/4885ALDH1A1 3041/4885L3MBTL1 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.