Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25841831 | 0.86 | POLB (0.64) | POLBLMNAPTGER4KDM4EALDH1A1 | |
| SCHEMBL23318256 | 0.85 | PTGER4 (0.50) | POLBLMNAPTGER4KDM4EALDH1A1 | |
| SCHEMBL22166473 | 0.84 | PTGER4 (0.54) | POLBLMNAPTGER4KDM4EALDH1A1 | |
| SCHEMBL23318342 | 0.82 | PTGER4 (0.49) | POLBLMNAPTGER4KDM4EALDH1A1 | |
| SCHEMBL29787117 | 0.81 | POLB (1.00) | POLBLMNAKDM4EALDH1A1GLA | |
| SCHEMBL29771433 | 0.81 | POLB (1.00) | POLBLMNAKDM4EALDH1A1GLA | |
| SCHEMBL153365 | 0.81 | POLB (1.00) | POLBLMNAKDM4EALDH1A1GLA | |
| SCHEMBL17513001 | 0.81 | KDM4E (0.54) | POLBLMNAPTGER4KDM4EALDH1A1 | |
| SCHEMBL4777741 | 0.81 | PTGER4 (0.48) | POLBLMNAPTGER4KDM4EALDH1A1 | |
| SCHEMBL4780038 | 0.80 | PTGER4 (0.51) | POLBLMNAPTGER4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696898-B2 | Reverse photochromic compound | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696898-B2 | Reverse photochromic compound | CRY1, CRY2, C3AR1 | POLB 2413/4885LMNA 1032/4885PTGER4 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.