Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834771 | 0.95 | S1PR1 (0.39) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL17532307 | 0.93 | PYGL (0.35) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL17532372 | 0.91 | F2 (0.34) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL19485602 | 0.91 | PRCP (0.38) | S1PR4S1PR1S1PR5S1PR3PRCP | |
| SCHEMBL16295882 | 0.90 | PYGL (0.38) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL16343488 | 0.90 | PYGL (0.38) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL17834454 | 0.90 | CYP3A4 (0.37) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL19485606 | 0.90 | CYP3A4 (0.37) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL17834844 | 0.90 | S1PR1 (0.35) | S1PR4S1PR1S1PR5S1PR3PYGL | |
| SCHEMBL17834841 | 0.90 | S1PR1 (0.35) | S1PR4S1PR1S1PR5S1PR3PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |