Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PLG | P00747 | 2/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.30 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22167260 | 0.95 | L3MBTL1 (0.32) | KLKB1L3MBTL1PRSS1F10PLG | |
| SCHEMBL22167229 | 0.94 | PLG (0.33) | L3MBTL1PRSS1F10PLGPRSS2 | |
| SCHEMBL22167413 | 0.94 | L3MBTL1 (0.33) | L3MBTL1PRSS1PLGPRSS2PRSS3 | |
| SCHEMBL17532357 | 0.94 | L3MBTL1 (0.33) | L3MBTL1PRSS1PLGPRSS2PRSS3 | |
| SCHEMBL17468487 | 0.92 | KIFC1 (0.34) | KIFC1 | |
| SCHEMBL17532368 | 0.92 | KIFC1 (0.34) | KIFC1 | |
| SCHEMBL19695867 | 0.92 | KIFC1 (0.34) | KIFC1 | |
| SCHEMBL17532330 | 0.91 | MME (0.32) | SRC | |
| SCHEMBL17532356 | 0.91 | MME (0.32) | SRC | |
| SCHEMBL17492932 | 0.90 | PSMB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |