Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468600 | 1.00 | FPR2 (0.34) | FPR2KMT2AHRH2HRH1ACACB | |
| SCHEMBL22384298 | 0.91 | ACACB (0.35) | FPR2KMT2AHRH2HRH1ACACB | |
| SCHEMBL16305977 | 0.91 | ACACB (0.35) | FPR2KMT2AHRH2HRH1ACACB | |
| SCHEMBL17459576 | 0.89 | PYGL (0.38) | FPR2ACACBNPC1TP53HPGD | |
| SCHEMBL17459574 | 0.89 | PYGL (0.38) | FPR2ACACBNPC1TP53HPGD | |
| SCHEMBL17468458 | 0.85 | MAPT (0.42) | KMT2A | |
| SCHEMBL17834369 | 0.85 | ACACB (0.41) | FPR2KMT2AHRH2HRH1ACACB | |
| SCHEMBL17468537 | 0.84 | FPR2 (0.34) | FPR2ACACBSMN1; SMN2ITGA4ITGB7 | |
| SCHEMBL17492936 | 0.84 | FPR2 (0.34) | FPR2ACACBSMN1; SMN2ITGA4ITGB7 | |
| SCHEMBL22384212 | 0.84 | ACACB (0.36) | FPR2KMT2AHRH2HRH1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |