Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 3/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384194 | 0.89 | CTSS (0.36) | ACACBHRH2HRH1KMT2ACTSS | |
| SCHEMBL22384298 | 0.85 | ACACB (0.35) | ACACBHRH2HRH1P2RX7KMT2A | |
| SCHEMBL17532278 | 0.85 | P2RX7 (0.52) | HRH2HRH1P2RX7KMT2ACTSK | |
| SCHEMBL16305977 | 0.85 | ACACB (0.35) | ACACBHRH2HRH1P2RX7KMT2A | |
| SCHEMBL22167308 | 0.84 | FPR2 (0.34) | ACACBHRH2HRH1P2RX7KMT2A | |
| SCHEMBL17468600 | 0.84 | FPR2 (0.34) | ACACBHRH2HRH1P2RX7KMT2A | |
| SCHEMBL22384328 | 0.83 | ACACB (0.34) | ACACBHRH2HRH1P2RX7CTSS | |
| SCHEMBL22756134 | 0.81 | MAPT (0.41) | KMT2ACTSSCTSKITGA4ITGB7 | |
| SCHEMBL17834369 | 0.79 | ACACB (0.41) | ACACBHRH2HRH1KMT2AMAPK1 | |
| SCHEMBL22167286 | 0.78 | ACACB (0.33) | ACACBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |