SCHEMBL22167635

SCHEMBL22167635

CNC(=O)C1(C(=O)O)CC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.38
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16847510 0.90 FFAR3 (0.35) FFAR3CYP3A4SMN1; SMN2THRB
Hydrochloric Acid SCHEMBL27925511 0.86 CYP3A4 (0.38) FFAR3CYP3A4SMN1; SMN2
SCHEMBL21636890 0.86 CYP3A4 (0.33) FFAR3CYP3A4SMN1; SMN2THRB
SCHEMBL18421736 0.83 NPSR1 (0.34) FFAR3CYP3A4
SCHEMBL25194719 0.79 DGAT1 (0.43) FFAR3
SCHEMBL2199488 0.77 KDM4E (0.39) CYP3A4SMN1; SMN2
SCHEMBL28668886 0.76 HDAC4 (0.38) FFAR3
SCHEMBL18472974 0.76 THRB (0.35) CYP3A4SMN1; SMN2THRB
SCHEMBL9911496 0.75 ALDH1A1 (0.42) FFAR3
SCHEMBL15731538 0.75 NPSR1 (0.39) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4522596-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X Discovery Limited (GB) 2025-03-19 EP disclosed
CN-119497712-A Indane derivatives as MALT1 inhibitors 希四克斯探索有限公司 2025-02-21 CN disclosed
WO-2023218203-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X DISCOVERY LIMITED (GB) 2023-11-16 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-3889154-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-10-06 EP disclosed
WO-2020135771-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2020-07-02 WO disclosed
CN-108473464-A The isoindoline ketone inhibitors of MDM2-P53 interactions with active anticancer 阿斯泰克斯治疗有限公司 2018-08-31 CN disclosed