Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | GLA | P06280 | 3/20 | 0.75 |
| ▸ | ACHE | P22303 | 3/20 | 0.75 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL1772714 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL4972293 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL3045498 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL29352289 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL8339 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL10827474 | 0.85 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL28646458 | 0.84 | ALDH1A1 (0.83) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL17141399 | 0.84 | ALDH1A1 (0.83) | ALDH1A1HPGDMAPTGLAACHE | |
| Anthracene SCHEMBL9879830 | 0.84 | MAPT (0.94) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL1551975 | 0.84 | ALDH1A1 (0.94) | ALDH1A1HPGDMAPTGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750528-A1 | COMPOSITIONS FOR TREATING DYSTROPHIES AND MYOTONIA | Nexien Biopharma, Inc. (US) | 2020-12-16 | — | — | EP | disclosed |
| US-10702495-B2 | Method and compositions for treating dystrophies and myotonia | NEXIEN BIOPHARMA, INC. (US) | 2020-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702495-B2 | Method and compositions for treating dystrophies and myotonia | MYOF, MYH2, MYLK2 | ALDH1A1 3113/4885HPGD 2714/4885MAPT 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.