Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127134 | 0.84 | ALDH1A1 (0.58) | ALDH1A1PKMMAPTGAAMEN1 | |
| SCHEMBL25366862 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1PKMMAPTGAAMEN1 | |
| SCHEMBL8898795 | 0.79 | PSMD14 (0.36) | ALDH1A1PKMMAPTGAAMEN1 | |
| SCHEMBL31595929 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1PKMMAPTGAAMEN1 | |
| SCHEMBL1770469 | 0.79 | NPC1 (0.46) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3254919 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL25369141 | 0.78 | PARP1 (0.39) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| Formamide SCHEMBL28482328 | 0.77 | ALDH1A1 (0.59) | ALDH1A1PKMMAPTGAAMEN1 | |
| SCHEMBL1748098 | 0.75 | ALDH1A1 (0.66) | ALDH1A1PKMMAPTGAAMEN1 | |
| SCHEMBL24928789 | 0.75 | MAPT (0.58) | ALDH1A1PKMMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265104-A1 | NOVEL HETEROCYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-08-24 | — | — | US | disclosed |
| CN-108101863-B | Method for synthesizing benzothiazole-2-ketone derivative by using carbonyl sulfide and disulfide as raw materials | 内蒙古工业大学 | 2022-01-25 | — | — | CN | disclosed |
| EP-3204352-B1 | INHIBITORS OF LYSINE GINGIPAIN | CORTEXYME INC (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-108101863-A | It is a kind of using carbonyl sulfur and disulphide as the method for Material synthesis benzothiazole -2- ketones derivants | 内蒙古工业大学 | 2018-06-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265104-A1 | NOVEL HETEROCYCLIC COMPOUNDS | MKI67, CCNI, KRAS | ALDH1A1 345/4885PKM 1992/4885MAPT 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.