Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.56 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824298 | 0.74 | CYP3A4 (0.66) | CYP3A4CYP2C19ALDH1A1TP53MEN1 | |
| SCHEMBL221735 | 0.73 | TP53 (0.47) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 | |
| SCHEMBL10196663 | 0.73 | POLB (0.76) | ALDH1A1TP53MEN1KMT2AMAPT | |
| SCHEMBL8599093 | 0.72 | MAPT (0.75) | CYP3A4CYP2C19ALDH1A1TP53MEN1 | |
| SCHEMBL2607592 | 0.71 | TP53 (0.56) | CYP3A4CYP2C19ALDH1A1TP53MEN1 | |
| SCHEMBL13182216 | 0.69 | KDM4E (0.67) | CYP3A4CYP2C19ALDH1A1TP53MEN1 | |
| SCHEMBL15643258 | 0.69 | APEX1 (0.71) | CYP3A4CYP2C19ALDH1A1TP53MEN1 | |
| SCHEMBL18363182 | 0.68 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL20989184 | 0.67 | LMNA (0.53) | TP53MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14487436 | 0.67 | APEX1 (0.60) | CYP2C19ALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10849840-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | NEW AVON LLC (US) | 2020-12-01 | — | — | US | disclosed |
| US-10849840-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | NEW AVON LLC (US) | 2020-12-01 | — | — | US | disclosed |
| EP-3272329-B1 | COMPOSITIONS AND METHODS FOR STIMULATION MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | AVON PROD INC (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-3272329-B1 | COMPOSITIONS AND METHODS FOR STIMULATION MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | AVON PROD INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20180271772-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | AVON PRODUCTS, INC | 2018-09-27 | — | — | US | disclosed |
| US-9999587-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | AVON PRODUCTS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9999587-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | AVON PRODUCTS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9999587-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | AVON PRODUCTS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| EP-3272329-A2 | COMPOSITIONS AND METHODS FOR STIMULATION MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | Avon Products, Inc. (US) | 2018-01-24 | — | — | EP | disclosed |
| EP-3272329-A2 | COMPOSITIONS AND METHODS FOR STIMULATION MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | Avon Products, Inc. (US) | 2018-01-24 | — | — | EP | disclosed |
| US-20160008266-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | CITIBANK, N.A., LONDON BRANCH | 2016-01-14 | — | — | US | disclosed |
| US-20160008266-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | CITIBANK, N.A., LONDON BRANCH | 2016-01-14 | — | — | US | disclosed |
| US-20160008266-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | CITIBANK, N.A., LONDON BRANCH | 2016-01-14 | — | — | US | disclosed |
| US-9132294-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | AVON PRODUCTS, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| US-9132294-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | AVON PRODUCTS, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2588593-A2 | COMPOSITIONS AND METHODS FOR STIMULATING MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | Avon Products, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012005876-A2 | COMPOSITIONS AND METHODS FOR STIMULATING MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | AVON PRODUCTS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20120003332-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | AVON PRODUCTS, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120003332-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | AVON PRODUCTS, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180271772-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | MAG, MFAP1, CUTA | CYP3A4 4877/4885CYP2C19 4859/4885ALDH1A1 4291/4885 |
| US-20160008266-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | MAG, MFAP1, CUTA | CYP3A4 4877/4885CYP2C19 4859/4885ALDH1A1 4291/4885 |
| US-10849840-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | MAG, MFAP1, CUTA | CYP3A4 4877/4885CYP2C19 4859/4885ALDH1A1 4291/4885 |
| US-20120003332-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | MAG, MFAP1, CUTA | CYP3A4 4877/4885CYP2C19 4859/4885ALDH1A1 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.