Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221734 | 0.73 | CYP3A4 (0.57) | TP53MEN1KMT2ANPSR1GAA | |
| SCHEMBL22055666 | 0.63 | LMNA (0.49) | MEN1KMT2APIK3CBPIK3CDPIK3CA | |
| SCHEMBL8568250 | 0.63 | PIK3CB (0.45) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL15723845 | 0.62 | KDM4E (0.58) | MEN1KMT2ANPSR1GAAMAPT | |
| SCHEMBL178443 | 0.60 | NCF1 (0.66) | MAPTALDH1A1 | |
| SCHEMBL14826491 | 0.59 | ALDH1A1 (0.70) | TP53MEN1KMT2ANPSR1MAPT | |
| SCHEMBL9431028 | 0.58 | TNF (0.74) | TP53MEN1KMT2ANPSR1TSHR | |
| SCHEMBL632013 | 0.58 | MMP8 (0.45) | MEN1KMT2ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL12021982 | 0.58 | HRH3 (0.73) | NPSR1TSHRMAPT | |
| SCHEMBL22040866 | 0.58 | L3MBTL1 (0.53) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9132294-B2 | Compositions and methods for stimulation MAGP-1 to improve the appearance of skin | AVON PRODUCTS, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2588593-A2 | COMPOSITIONS AND METHODS FOR STIMULATING MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | Avon Products, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012005876-A2 | COMPOSITIONS AND METHODS FOR STIMULATING MAGP-1 TO IMPROVE THE APPEARANCE OF SKIN | AVON PRODUCTS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20120003332-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | AVON PRODUCTS, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003332-A1 | Compositions and Methods for Stimulation MAGP-1 to Improve the Appearance of Skin | MAG, MFAP1, CUTA | TP53 4379/4885MEN1 1939/4885KMT2A 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.