SCHEMBL22174649

SCHEMBL22174649

Cc1ccc(C)c2sc(-c3ccc(-c4ccccc4)cc3)nc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.49
RARB P10826 2/20 0.49
RARG P13631 2/20 0.49
ADORA3 P0DMS8 3/20 0.46
ADORA2A P29274 3/20 0.46
ADORA1 P30542 3/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
ALOX5 P09917 1/20 0.44
ALDH1A1 P00352 5/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
HPGD P15428 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
LMNA P02545 3/20 0.41
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 1/20 0.41
COMT P21964 1/20 0.41
CCR6 P51684 1/20 0.41
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18873092 0.96 ADORA3 (0.49) RARARARBRARGADORA3ADORA2A
SCHEMBL27307687 0.87 ADORA3 (0.46) RARARARBRARGADORA3ADORA2A
SCHEMBL21474633 0.86 RARA (0.48) RARARARBRARGSMN1; SMN2ALOX5
SCHEMBL21533341 0.83 APP (0.46) RARARARBRARGALOX5GAA
SCHEMBL8534672 0.83 GAA (0.52) RARARARBRARGADORA3ADORA2A
SCHEMBL21474669 0.81 PIK3CD (0.44) RARARARBRARGSMN1; SMN2ALDH1A1
SCHEMBL17059008 0.80 APP (0.49) RARARARBRARGSMN1; SMN2ALDH1A1
SCHEMBL17059006 0.79 APP (0.44) RARARARBRARGALDH1A1KDM4E
SCHEMBL21474664 0.79 CYP3A4 (0.52) SMN1; SMN2ALOX5NPC1RAB9ANPSR1
SCHEMBL20349639 0.79 NPC1 (0.49) RARARARBRARGSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3674757-B1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICAL ANISOTROPIC BODY, POLARIZER, ANTIREFLECTIVE FILM, DISPLAY DEVICE AND METHOD FOR MANUFACTURING POLYMERIZABLE LIQUID CRYSTAL COMPOSITION ZEON CORP (JP) 2022-04-20 EP disclosed
EP-3674757-A1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICAL ANISOTROPIC BODY, POLARIZER, ANTIREFLECTIVE FILM, DISPLAY DEVICE AND METHOD FOR MANUFACTURING POLYMERIZABLE LIQUID CRYSTAL COMPOSITION Zeon Corporation (JP) 2020-07-01 EP disclosed