Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474633 | 0.86 | RARA (0.48) | GAAGLATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL22174649 | 0.83 | RARA (0.49) | GAAGLATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL21533341 | 0.83 | APP (0.46) | GAATP53APPRARARARB | |
| SCHEMBL18873092 | 0.82 | ADORA3 (0.49) | GAASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL20349615 | 0.81 | RARA (0.44) | GAAGLATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL21474669 | 0.81 | PIK3CD (0.44) | GAASMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL17059008 | 0.80 | APP (0.49) | GAAGLATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL20349639 | 0.79 | NPC1 (0.49) | GAASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL17059006 | 0.79 | APP (0.44) | GAAALDH1A1APPKDM4ERARA | |
| SCHEMBL17059009 | 0.78 | RARA (0.45) | GAAGLATP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581245-B1 | Water-insoluble azo colouring agents | CLARIANT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5428136-A | Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component | HOECHST AG (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0581245-A1 | Water-insoluble azo colouring agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |