Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21125765 | 0.98 | MAOB (0.34) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL21264461 | 0.94 | MAOB (0.35) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL22175302 | 0.92 | MEN1 (0.36) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL14732274 | 0.92 | KMT2A (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL21636032 | 0.88 | MAOB (0.40) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL21636126 | 0.88 | MAOB (0.40) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL22022438 | 0.88 | MAOB (0.40) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL21142693 | 0.88 | MAOB (0.40) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL26042857 | 0.88 | MAOB (0.40) | MAOBBRD4TSPOMEN1KMT2A | |
| SCHEMBL20633277 | 0.88 | MAOB (0.42) | MAOBBRD4TSPOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | MAOB 2037/4885BRD4 932/4885TSPO 875/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | MAOB 2037/4885BRD4 932/4885TSPO 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.