Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CDA | P32320 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684264 | 0.78 | — | — | |
| SCHEMBL20183786 | 0.73 | — | — | |
| SCHEMBL30598229 | 0.71 | — | — | |
| SCHEMBL30598233 | 0.71 | — | — | |
| SCHEMBL11809519 | 0.69 | — | — | |
| SCHEMBL14140476 | 0.69 | — | — | |
| SCHEMBL14817456 | 0.68 | LMNA (0.37) | LMNAGBA1 | |
| SCHEMBL346819 | 0.67 | LMNA (0.44) | LMNAGBA1CDA | |
| SCHEMBL504610 | 0.67 | LMNA (0.44) | LMNAGBA1CDA | |
| SCHEMBL6287151 | 0.67 | LMNA (0.39) | LMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969405-B2 | Anticancer compounds and methods of making and using same | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969405-B2 | Anticancer compounds and methods of making and using same | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969405-B2 | Anticancer compounds and methods of making and using same | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2015-03-03 | — | — | US | disclosed |
| US-20110178098-A1 | ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2011-07-21 | — | — | US | disclosed |
| US-20110178098-A1 | ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2011-07-21 | — | — | US | disclosed |
| US-20110178098-A1 | ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2011-07-21 | — | — | US | disclosed |
| WO-2009155606-A1 | ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009155606-A1 | ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178098-A1 | ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME | MKI67, MCL1, BAD | LMNA 1053/4885GBA1 433/4885CDA 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.